Pediatric Diabetes

 Incidence and prevalence trends of youth-onset type 2 diabetes in a cohort of Canadian youth: 2002-2013
 
Objective Youth-onset type 2 diabetes is an emerging disease. We estimated incidence and prevalence trends of youth-onset type 2 diabetes between 2002 and 2013 in the Canadian province of British Columbia. Methods This population-based cohort study used a validated diabetes case-finding definition and algorithm to differentiate type 2 from type 1 diabetes to identify youth <20 years with type 2 diabetes within linked population-based administrative data. Age-standardized incidence and prevalence were calculated. JoinPoint regression and double exponential smooth modeling were used. Results From 2002/2003 to 2012/2013, the incidence of youth-onset type 2 diabetes increased from 3.45 (95% confidence interval, CI: 2.43, 4.80) to 5.16 (95% CI: 3.86, 6.78)/100?000. The annual percent change (APC) in incidence was 3.74 (95% CI: 1.61, 5.92; P?=?0.003) overall, while it was 5.94 (95% CI: 1.84, 10.20; P?=?0.009) and 0.53 (95% CI: ?5.04, 6.43; P?=?0.837) in females and males, respectively. The prevalence increased from 0.009% (95% CI: 0.007, 0.011) in 2002/2003 to 0.021% (95% CI: 0.018, 0.024) in 2012/2013 with an APC of 7.89 (95% CI: 6.41, 9.40; P?